Chief Commercial Officer

Summit Therapeutics Open · verified Sep 14, 2026

Princeton C-Suite Sales Leadership

Leadership Sales Leadership role at Summit Therapeutics. Princeton · $400,000–$480,000 base.

SalaryStated by Summit Therapeutics

$400,000 – $480,000

Base salary for this role, in USD per year, as published in the posting.

Role brief

Growth Roles summary, based on the employer's posting.

What you'll do

You'll shape ivonescimab's commercial strategy and lead its growth across international markets
You'll guide pricing, reimbursement, and health economics work to improve access and market penetration
You'll build and manage sales and marketing organizations with goals, metrics, and incentive plans
You'll direct product launches, keeping execution aligned with regulatory rules and market needs
You'll pursue partnerships, manage commercial resources, and use market intelligence to find growth opportunities

What you bring

A bachelor's degree in business, marketing, life sciences, or a related discipline
At least fifteen years in pharmaceutical or biotechnology commercial leadership, including NSCLC/NDCLC and solid tumors
Experience launching blockbuster drugs in NSCLC/NDCLC or solid tumors within the past five years
A record of bringing pharmaceutical products to market globally
Strength in market access, strategic partnerships, leadership, analysis, and stakeholder communication

Who this fits

You'll suit an executive commercial leader who can operate in a fast-moving environment, adjust to market changes, and work across functions. The role is based in Princeton, United States, and includes travel of up to 50%. You’ll join the executive leadership team and oversee global commercialization.

From the employer

About Summit:

Summit Therapeutics Inc. is a biopharmaceutical oncology company with a mission focused on improving quality of life, increasing potential duration of life, and resolving serious unmet medical needs. At Summit, we believe in building a team of world class professionals who are passionate about this mission, and it is our people who drive this mission to reality. Summit’s core values include integrity, passion for excellence, purposeful urgency, collaboration, and our commitment to people. Our employees are truly the heart and soul of our culture, and they are invaluable in shaping our journey toward excellence.

Summit’s team is inspired to touch and help change lives through Summit’s clinical studies in the field of oncology. Summit has multiple global Phase 3 clinical studies, including:

Non-small Cell Lung Cancer (NSCLC)

HARMONi: Phase 3 clinical study which was intended to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR-mutated, locally advanced or metastatic non-squamous NSCLC who were previously treated with a 3rd generation EGFR TKI.

HARMONi-3: Phase 3 clinical study which is intended to evaluate ivonescimab combined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with first-line metastatic NSCLC.

HARMONi-7: Phase 3 clinical study which is intended to evaluate ivonescimab monotherapy compared to pembrolizumab monotherapy in patients with first-line metastatic NSCLC.

Colorectal Cancer (CRC)

HARMONi-GI3: Phase 3 clinical study intended to evaluate ivonescimab in combination with chemotherapy compared with bevacizumab plus chemotherapy.

Ivonescimab is an investigational therapy not presently approved by any regulatory authority other than China’s National Medical Products Administration (NMPA). Summit is headquartered in Miami, Florida, and has additional offices in California, New Jersey, the UK, and Ireland.

Overview of Role:

The Chief Commercial Officer (CCO) will be a key member of the executive leadership team, responsible for
developing and executing the company's commercial strategy. This role will oversee all aspects of
commercialization, including market access, sales, marketing, and distribution. The CCO will work closely with
cross-functional teams to ensure successful product launches and sustainable growth in global markets.

Role and Responsibilities:

Develop and execute a comprehensive commercial strategy for ivonescimab and drive the successful
launch and growth of the company's products in global markets
Lead market access strategies, including pricing, reimbursement, and health economics, to ensure
optimal market penetration and patient access
Build and lead high-performing sales and marketing teams, establishing clear goals, performance
metrics, and incentive programs that align with the Company’s values and strategic deliverables
Oversee the planning and execution of product launches, ensuring alignment with regulatory
requirements and market needs
Identify and pursue strategic partnerships, alliances, and licensing opportunities to expand the
company's commercial footprint
Foster strong relationships with key stakeholders, including healthcare providers, payers, and patient
advocacy groups
Develop and manage the commercial budget, ensuring efficient allocation of resources to achieve
commercial objectives
Monitor market trends, competitive landscape, and customer insights to inform strategic decisionmaking and identify growth opportunities
Ensure all commercial activities comply with relevant regulations and industry standards
All other duties as assigned

Experience, Education and Specialized Knowledge and Skills:

Bachelor’s degree in business, Marketing, Life Sciences, or a related field; MBA or advanced degree
preferred
Minimum of 15+ years of experience in commercial leadership roles within the pharmaceutical or
biotechnology industry, with direct experience in NSCLC/NDCLC and solid tumors
Experience with blockbuster drug commercial launches in NSCLC/NDCLC and/or solid tumors within
the past 5 years
Proven track record of successfully launching and commercializing pharmaceutical products in global
markets
Strong strategic thinking and analytical skills, with the ability to translate market insights into
actionable strategies
Excellent leadership and team-building skills, with a demonstrated ability to inspire and motivate crossfunctional teams
Exceptional communication and interpersonal skills, with the ability to build and maintain relationships
with key stakeholders
In-depth knowledge of market access, pricing, reimbursement, and health economics.
Experience in business development and strategic partnerships
Ability to thrive in a fast-paced, dynamic environment and adapt to changing market conditions
Travel up to 50%

This is the pay for this position

Pay Transparency$400,000—$480,000 USD

Actual compensation packages are based on several factors that are unique to each candidate, including but not limited to skill set, depth of experience, certifications, and specific work location. This may be different in other locations due to differences in the cost of labor. The total compensation package for this position may also include bonus, stock, benefits and/or other applicable variable compensation.

Summit does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact Summit’s Talent Acquisition team at recruiting@smmttx.com to obtain prior written authorization before referring any candidates to Summit.

Summit Therapeutics Inc. is an Equal Opportunity Employer and takes pride in creating and maintaining diverse environment. We do not discriminate in recruitment, hiring, training or promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.